SINCE World war 2, medical science has progressed into a stage where competitive medications are available to treat the same ailment in numerous people. This is simply not almost brands (the industry trade issue) but generic drugs (the industry scientific issue). On this report, we shall go through the various factors that decide picking a a certain drug.
Safety: The subsequent sub-criteria has to be considered under the criterion of safety:
* Acute therapeutic index: When the patient’s condition is acute, how effective is often a particular drug even though it’s certain side-effects providing the acuteness in the condition is lowered? Example: narcotic pain-killers are very effective in healing pain but include the possibility side-effect of addiction.
* Long-term safety: medicationdirectory.com might be safe in short-term treatment, but wait, how safe it can be in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but tend to have undesirable effects in case there is prolonged use.
* Drug-drug interaction risk: Prescription medication is chemicals, and several chemicals reply to produce a different chemical, which has an effect that may harm the individual or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to make a new condition that warrants separate treatment.
Drug-drug interaction risk is of two kinds:
· Pharmacokinetic: In this kind of drug-drug interaction, two drugs, independent of the other person, have certain effects using one or maybe more body processes (e.g., metabolism) that affects the performance in the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the act of a liver enzyme that Lexapro (escitalopram) depends on because of its metabolism. This leads to more the side-effects of Lexapro.
· Pharmacodynamic: Here, a couple of drugs actually make the same impact on the same organ, thus increasing the total, added effect. Example: Lexapro has certain side-effects such as drowsiness and fatigue. Darvocet-N also acts similarly about the brain. Thus, the side-effects of the two prescription medication is more intense.
Tolerability: A medication might be effective but not tolerable by all patients. Example: Allergies to certain drugs in most people. Short-term and long-term tolerability have to be considered. Efficacy: A medication is not equally great at all patients. For example, some patients with depression or panic attacks experience reduced escitalopram, but there are many that don’t, who therefore have to be prescribed a different anti-depressant. The speed of onset of therapeutic action is a crucial key to be regarded too.
Cost: Cost doesn’t imply the price of acquisition of a certain medicine alone. It will also cover the price of treatments for a complication that may arise from using a different drug. Example: In a person who insists on taking alcohol but must be treated for depression is generally administered an SSRI drug since these drugs don’t potentiate the consequences of alcohol, whereas another gang of anti-depressants (such as tricyclics) can cause a fresh symptom in such patients, which may demand a various and expensive treatment. Therefore, it’s safer to prescribe the more expensive escitalopram as opposed to a cheaper tricyclic in these patients.
Simple treatment: The best mode of administration is preferred. If you find an option between an injection and oral administration, aforementioned is preferred in the event the efficacy of the two modes is comparable. Or, local application is preferred to the oral route where possible; e.g., antibiotic treatments for eye infections. Dosage and frequency of administration too are a key factor to decide simplicity of treatment.
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